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Six members of the same family, including four children, were killed in an overnight fire inNew YorkCity’s historic Harlem neighborhood. It is the deadliest fire in the city since 13 people werekilled in a Bronx fire in late 2017.

The fire broke out on the fifth floor of the building in East Harlem at the intersection of Adam Clayton Powell Boulevard and 142nd Street at about 1:45 a.m. on Wednesday.

Officials said that all six people — two adults, two boys and two girls — were from the same family. All were pronounced dead on the scene.

The children range in age from 3 to 11, the fire department said. One of the adults is the children’s mother, while the second adult is her stepbrother.

driving  street PHOTO: Six people from the same family, including four children, were killed in a fire at 142nd Street in Harlem, N.Y., on Wednesday, May 8, 2019.
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Six people from the same family, including four children, were killed in a fire at 142nd Street in Harlem, N.Y., on Wednesday, May 8, 2019.

The fire did not appear to be suspicious, but an investigation is underway, fire officials said. Early indications are that the burn on the stove may have been left on overnight, a source told ABC News.

“Units were met at the door of that apartment with fire. The entire apartment was involved,” Fire Commissioner Daniel Nigro said. “They aggressively moved in, extinguishing the fire as they did. When they reached the two rear bedrooms we found six occupants of that apartment deceased.”

It took about an hour to get the fire under control, Nigro said.

“As aggressive as those members could be, they were not able to reach those occupants,” Nigro said of his firefighters.

The building is part of the Frederick E. Samuel Houses, a city-owned housing complex.

ABC News’ Will Gretsky contributed to this report.

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